After coming off a tough loss to Toronto in which the Red Sox bats were virtually silent throughout most of the game, Jon Lester will certainly be happy to face the Baltimore Orioles tonight.

Lester, who is 8-0 lifetime against the Orioles with a 2.18 ERA, will be looking to keep his perfect streak alive as he faces off against Jeremy Guthrie, who is 1-2 with a 4.01 ERA in nine games against Boston. Guthrie’s last start at Fenway came on April 17 when he allowed 8 runs in 4 2/3 innings.

The Red Sox are 7-1 this season against Baltimore, who currently occupy last place in the AL East. Boston, who held a three-game lead over the second-place Yankees before the All-Star break, is now trailing New York by 2.5 games.

ORIOLES VS. JON LESTER

Nick Markakis (29 career plate appearances against Lester): .250 average/ .276 OBP/ .393 slugging, walk, 7 strikeouts

Brian Roberts (28): .240/ .321/ .480, homer, 3 walks, 6 strikeouts

Aubrey Huff (27): .320/ .370/ .560, homer, 2 walks, 5 strikeouts

Melvin Mora (21): 3-for-20, walk, 4 strikeouts

Adam Jones (18): 5-for-15, 3 walks, 3 strikeouts

Gregg Zaun (9): 1-for-7, 2 walks, 3 strikeouts

Luke Scott (8): 0-for-8, 3 strikeouts

Ty Wigginton (8): 4-for-8, strikeout

Robert Andino (4): 3-for-4

Nolan Reimold (3): 1-for-3, strikeout

Matt Wieters (3): 1-for-3, strikeout

Felix Pie (2): 0-for-2, strikeout

RED SOX VS. JEREMY GUTHRIE

Kevin Youkilis (26 career plate appearances against Guthrie): .182 average/ .308 OBP/ .227 slugging, 4 walks, 7 strikeouts

Dustin Pedroia (21): .389/ .476/ .500, 3 walks, strikeout

Mike Lowell (19): 3-for-17, homer, 2 walks, strikeout

David Ortiz (19): 5-for-17, walk, 4 strikeouts

J.D. Drew (17): 5-for-14, homer, 3 walks, 2 strikeouts

Jacoby Ellsbury (17): 4-for-16, walk, strikeout

Jason Varitek (15): 4-for-14, homer, walk, 4 strikeouts

Jason Bay (6): 3-for-5, 2 homers, walk, strikeout

Rocco Baldelli (4): 0-for-4

Nick Green (3): 1-for-3

Jed Lowrie (3): 0-for-3, strikeout