Clay Buchholz

Clay Buchholz (10-4, 2.47) gets the ball Saturday as he leads the Red Sox against the Giants in the middle game of the final interleague series of the Sox’ season. In his most recent victory, June 20 against the Dodgers, Buchholz pitched 6 2/3 scoreless innings, allowing just three hits while striking out four. It was win No. 10 for the righty, making him one of only five pitchers in the majors with double-digit wins this season.

Saturday marks Buchholz’ first matchup ever against the Giants. He has only faced four players on the Giants’ active roster: Aubrey Huff, Pat Burrell, Edgar Renteria and Juan Uribe. That group is a combined 3-for-20 (.150 average) against him.

Buchholz will be opposed by Madison Bumgarner, the Giants pitching prospect who is being summoned on Saturday for his first big league outing of the 2010 season. The 20-year-old, who was selected in the first round of the 2007 draft, was 7-1 with a 3.16 ERA with Triple-A Fresno this season — the only level where he’s ever had an ERA over 2.00. In his minor league career, he has a startling 34-6 record with a 2.00 ERA and 8.0 strikeouts per nine innings, though there had been concerns that his velocity had dipped from the low-90s to the mid- to high-80s last season and in spring training.

In four appearances last year (one start), he did not record a decision and allowed just two runs for a 1.80 ERA. No Red Sox hitter has faced Bumgarner.

Giants vs. Clay Buchholz

Aubrey Huff (12 career plate appearances): .222 average/.333 OBP/.333 slugging, 2 hits, 1 double, 2 RBI, 2 walks, 1 strikeout

Pat Burrell (8): .143/.250/.286, 1 hit, 1 double, 3 RBIs, 1 walk, 1 strikeout

Edgar Renteria (2): .000/.000/.000

Juan Uribe (2): .000/.000/.000

The Sox starter has never faced Travis Ishikawa, Bengie Molina, Buster Posey, Aaron Rowand, Freddy Sanchez, Pablo Sandoval, Nate Schierholtz, Andres Torres and Eli Whiteside.